Genome assembly produces the raw genomic sequence of an organism. Genome annotation adds meaning to sequence by associating structural and functional annotation with specific regions (loci) on the genome. This workshop will introduce genome annotation in the context of small genomes. We'll begin with genome annotation concepts, and then introduce resources and tools for automatically annotating small genomes. The workshop will finish with a review of options for further automatic and manual tuning of the annotation, and for maintaining it as new assemblies or information becomes available.